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Title: Evaluation of Antioxidant Activity, Free Radical Scavenging and Cuprac of Two Compounds Isolated from Scorzonera Undulata Ssp Deliciosa
Authors: Harkati Brahim; Akkal Salah; Bayet Christine; Laouer Hocine; Dijoux-Franca M-G
Aff: Laboratoire des molécules actives et applications, Université Tébessa, Route de Constantine 12000 Tébessa, Algérie.
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Keywords: Antioxidant Activity; Cuprac; DPPH; Scorzonera Undulata; Galangustin; Acteoside.
Abstract:Known for its medicinal, aromatic and culinary properties, the Asteraceae family has a major economic interest, such as a source of natural compounds. As part of the study of biodiversity of Algerian flora, a phytochemical analysis and research of biological activities of roots of Scorzonera undulata ssp deliciosa (Guss.) Maire were undertaken. Dichloromethane and methanol extracts led to the isolation of the known triterpenoid compounds such as: â acetate Amyrin, of them was known compounds (a mixture methyl Oleanate, methyl Ursolate and Stigmasterol, â-Sitosterol) and three phenolic derivatives among which two were new from the genus Scorzonera named: Galangustin and Acteoside and coumarin: Coumarin-O-â-glycoside were also isolated. The structures and relative configurations of the compounds were elucidated by MS and a series of 1D and 2D NMR analyses. Two pure compounds (Galangustin and Acteoside have been evaluated for their antioxidant activities through different methods: 1,1-diphenyl-2-picrylhydrazyl (DPPH) and cupric reducing antioxidant capacity (CUPRAC) methods demonstrated important radical scavenging activity with the antiradical power (ARP) of 5 (in DPPH method), and trolox equivalent antioxidant capacity (TEAC) = 1.